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CAS:86044-76-0|Acetyl-(D-Trp1,D-Phe(4-Cl)2,D-Trp3,D-Arg6,D-Ala10)-LHRH|Ac-w-chloro-fwSYrLRPa-NH2

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Liven Qian(钱叶华)-Custom Peptide
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ChinaPeptides Co., Ltd./强耀生物科技有限公司

NameAcetyl-(D-Trp1,D-Phe(4-Cl)2,D-Trp3,D-Arg6,D-Ala10)-LHRH
Code[86044-76-0]
The aliasAcetyl-(D-Trp1,D-Phe(4-Cl)2,D-Trp3,D-Arg6,D-Ala10)-LHRH
Sequence (single letter abbreviation)Ac-w-chloro-fwSYrLRPa-NH2
Sequence (three-letter abbreviation)Ac-D-Trp-4-chloro-D-Phe-D-Trp-Ser-Tyr-D-Arg-Leu-Arg-Pro-D-Ala-NH2(trifluoroacetate salt)
A basic descriptionAs a potent LHRH agonist, histrelin stimulates LH and FSH release and inhibits the actions of sex steroids on the male and female reproductive tracts. Its potency in vivo and in vitro is similar to that of the D-Trp6-containing analog. Especially because of its high water solubility and greater lipophilic character, histrelin appears promising for clinical application.Slow-release implants containing histreline implants were approved for the palliative treatment of advanced hormone-dependent prostate cancer.
solubility
The molecular weight1457.1
Chemical formulaC55H75N17O13
The purity80%，90%，95%，98%，99%
Weight1mg,5mg,10mg,50mg,100mg,1g
Storage conditionsStore at -20°C. Keep tightly closed. Store in a cool dry place.
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CAS:85466-18-8|Thymopoietin II (32-35)|RKDV

Contact： Liven Qian(钱叶华)-Custom Peptide Mobile: 13761298676（微信） Email：cps037@chinapeptides.net QQ：2880526724 ChinaPeptides Co., Ltd./强耀生物科技有限公司 Name Thymopoietin II (32-35) Code [85466-18-8] The alias Thymopoietin II (32-35) Sequence (single letter abbreviation) RKDV Sequence (three-letter abbreviation) H-Arg-Lys-Asp-Val-OH (trifluoroacetate salt) A basic description TP-4 and TP-3; shortest active thymopoietin II fragments described that exhibit potent immunoregulatory properties in vitro and in vivo. solubility The molecular weight 516.6 Chemical formula C21H40N8O7 The purity 80%，90%，95%，98%，99% Weight 1mg,5mg,10mg,50mg,100mg,1g Storage conditions Store at -20°C. Keep tightly closed. Store in a cool dry place. Number of Residues: 4 1-Letter Code: RKDV 3-Letter Code: Arg-Lys-Asp-Val Molecular weight (Mr): 516.6 g/mol Isoelectric point: 10.1 Net charge at pH 7.0: 1.0 Average hydrophilicity: 1.9 Ratio of hydrophilic residues / total number of residues...
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β-Amyloid (1-42), human|DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

Contact： Liven Qian(钱叶华)-Custom Peptide Mobile: 13761298676（微信） Email：cps037@chinapeptides.net QQ：2880526724 ChinaPeptides Co., Ltd./强耀生物科技有限公司   04010011526 β-Amyloid (1-42), human DAEFRHDSGYEVHHQKLVFFAEDV GSNKGAIIGLMVGGVVIA Number of Residues: 42 1-Letter Code: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA 3-Letter Code: Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala Molecular weight (Mr): 4513.12 g/mol Isoelectric point: 5.8 Net charge at pH 7.0: -1.7 Average hydrophilicity: -0.1 Ratio of hydrophilic residues / total number of residues: 31 %    Name beta-Amyloid (1-42), recombinant Code   The alias beta-Amyloid (1-42), recombinant Sequence (single letter abbreviation) DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA Sequence (three-letter abbreviation) H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-...
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The therapeutic effect of anti-CD52 treatment in murine experimental autoimmune encephalomyelitis is associated with altered IL-33 and ST2 expression levels

文献作者：Mark Barbour, Rachel Wood, Shehla U.Hridi, Chelsey Wilson, Grant McKay, Trevor J.Bushell, Hui-Rong Jiang   《Journal of Neuroimmunology》 ABSTRACTS Experimental autoimmune encephalomyelitis  (EAE) mice were administered with murine anti-CD52  antibody  to investigate its therapeutic effect and whether the treatment modulates IL-33 and ST2 expression. EAE severity and  central nervous system  (CNS) inflammation were reduced following the treatment, which was accompanied by peripheral  T and B lymphocyte  depletion and reduced production of various  cytokines  including IL-33, while sST2 was increased. In spinal cords of EAE mice, while the number of IL-33 +  cells remained unchanged, the extracellular level of IL-33 protein was significantly reduced in anti-CD52 antibody treated mice compared with controls. Furthermore the number of ST2 +  cells in the spinal cord of treated EAE mice was  downregulated ...
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