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LL-37
LLGDFFRKSKEKIGKEFKRIVQRI KDFLRNLVPRTES
Number of Residues: | 37 |
1-Letter Code: | LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES |
3-Letter Code: | Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser |
Molecular weight (Mr): | 4493.33 g/mol |
Isoelectric point: | 11.1 |
Net charge at pH 7.0: | 6.0 |
Average hydrophilicity: | 0.6 |
Ratio of hydrophilic residues / total number of residues: | 54 % |
Name | LL-37 |
Code | [154947-66-7] |
The alias | LL-37 |
Sequence (single letter abbreviation) | LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES |
Sequence (three-letter abbreviation) | H-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH (trifluoroacetate salt) |
A basic description | LL-37 amide is an antimicrobial peptide with angiogenic activity. |
solubility | |
The molecular weight | 4493.33 |
Chemical formula | C205H340N60O53 |
The purity | 80%,90%,95%,98%,99% |
Weight | 1mg,5mg,10mg,50mg,100mg,1g |
Storage conditions | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
Annotation | |
Documents | |
Figures | |
Reference | Z.Oren et al., Biochem. J., 341, 501 (1999) R.Koczulla et al., J. Clin. Invest., 111, 1665 (2003) R.Shaykhiev et al., Am. J. Physiol. Lung Cell. Mol. Physiol., 289, L842 (2005) J.D.Heilborn et al., Int. J. Cancer, 114, 713 (2005) G.H. Gudmundsson et al.,Eur. J. Biochem., 238, 325 (1996) R. Bals et al., Cell. Mol. Life Sci., 60, 711 (2003) M. Zanetti, J. Leukoc. Biol., 75, 39 (2004) P.T. Liu et al., Science, 311, 770 (2006) R. Lande et al., Nature, 449, 564 (2007) P.Y. Ong et al., New Engl. J. Med., 347, 1151 (2002) D.W. Hoskin et al., Biochim. Biophys. Acta, 1778, 357 (2008) Y.P. Lai et al., Trends Immunol., 30, 131 (2009) M.F. Burton et al., Nat. Prod. Rep., 26, 1572 (2009) |
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