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Hepcidin protects grass carp (Ctenopharyngodon idellus) against Flavobacterium columnare infection via regulating iron distribution and immune gene expression

Author：Xiaolei Wei, V.Sarath Babu, Li Lin, Yazhen Hu, Yulei Zhang, Xiaoling Liu, Jianguo Su, Jun Li, Lijuan Zhao, Gailing Yuan   《Fish & Shellfish Immunology》

ABSTRACTS
Columnaris disease (CD) caused by Flavobacterium columnare (F. columnare) is lack of knowledge on effective treatment measures. Bacterial pathogens require iron as an essential nutrient to infect the host. While hepcidin acts as a master regulator in iron metabolism, its contribution to host defense is emerging as complex and multifaceted. 
KEY WORDS
Hepcidin; Protective effect; Flavobacterium columnare; Ctenopharyngodon idellus; 
SCREENSHOT

RELATED PRODUCTS
CiHep mature peptide (QSHLSLCRYCCNCCRNKGCGYCCKF) was synthesized by a peptide synthesizer from ChinaPeptides (Shanghai, China) and analyzed by HPLC that the purity was >96.84
CHAINING
https://www.sciencedirect.com/science/article/pii/S1050464818300858

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