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CAS:163913-87-9|Myelin Oligodendrocyte Glycoprotein (MOG35-55), rat, mouse|MEVGWYRSPFSRVVHLYRNGK

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MOG(35-55)
MEVGWYRSPFSRVVHLYRNGK
Number of Residues:21
1-Letter Code:MEVGWYRSPFSRVVHLYRNGK
3-Letter Code:Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys

Molecular weight (Mr):2581.99 g/mol
Isoelectric point:10.6
Net charge at pH 7.0:3.1
Average hydrophilicity:-0.1
Ratio of hydrophilic residues / total number of residues:38 %


NameMyelin Oligodendrocyte Glycoprotein (MOG 35-55), rat, mouse
Code[163913-87-9]
The aliasMyelin Oligodendrocyte Glycoprotein (MOG 35-55), rat, mouse
Sequence (single letter abbreviation)MEVGWYRSPFSRVVHLYRNGK
Sequence (three-letter abbreviation)H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH (trifluoroacetate salt)
A basic descriptionIn contrast to the encephalitogenic rat homolog, this peptide is not a major T-cell epitope in multiple sclerosis propably due to its lower amount of helical structure formed when dissolved in micellar sodium dodecyl sulfate. This peptide induced anti-MOG(35-55) autoantibody production in C57BL/6 mice.
solubility
The molecular weight2581.9
Chemical formulaC118H177N35O29S1
The purity80%,90%,95%,98%,99%
Weight1mg,5mg,10mg,50mg,100mg,1g
Storage conditionsStore at -20°C. Keep tightly closed. Store in a cool dry place.
Annotation
Documents
Figures
ReferencePRODUCT CITATIONS: Le Moan, Natacha, et al. Eneuro 2.2 (2015): ENEURO-0050. Dupree, Jeffrey L., et al. Journal of Neurochemistry 134.2 (2015): 302-314. Orozco, Juan L. Hancke, and Rafael Burgos. U.S. Patent No. 9,060,994. 23 Jun. 2015. Polak, Paul E., et al. Journal of Neuroimmunology 276.1 (2014): 135-141. Rowse, Amber L., et al. PloS One 7.12 (2012): e52658. Sestero, Christine M., et al. The Journal of Immunology 189.6 (2012): 2918-2930. Wang, John Hsien. Diss. The University of Alabama at Birmingham, 2009. Naves, Rodrigo, et al. The Journal of Immunology 191.6 (2013): 2967-2977. Boullerne, Anne I., et al. Journal of neurochemistry 129.4 (2014): 696-703.

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