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CAS:141758-74-9|Exendin-4|HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2

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Exendin-4
HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2
NameExendin-4
Code[141758-74-9]
The aliasExendin-4
Sequence (single letter abbreviation)HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2
Sequence (three-letter abbreviation)H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2?(trifluoroacetate salt)
A basic descriptionA new member of the Glucagon superfamily that was originally isolated from the venom of the lizard, Heloderma Horridum. At low concentrations, it interacts with putative exendin receptors causing an increase in pancreatic acinar cAMP, while at higher concentrations it interacts with VIP receptors to stimulate an increase in cellular cAMP and amylase release.
solubility
The molecular weight4186.7
Chemical formulaC184H282N50O60S1
The purity80%，90%，95%，98%，99%
Weight1mg,5mg,10mg,50mg,100mg,1g
Storage conditionsStore at -20°C. Keep tightly closed. Store in a cool dry place.
Annotation
Documents
Figures
ReferenceJ. Eng et al., J. Biol. Chem., 267(11), 7402 (1992) 


Number of Residues:
39
1-Letter Code:HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2
3-Letter Code:His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

Molecular weight (Mr):4186.63 g/mol
Isoelectric point:4.8
Net charge at pH 7.0:-1.9
Average hydrophilicity:0.2
Ratio of hydrophilic residues / total number of residues:41 %


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