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CAS:124447-81-0|Amylin (1-37), rat|KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY-NH2 (Disulfide bridge)

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Amylin (1-37), rat, mouse+二硫键
KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY-NH2 (Disulfide bridge:C2-C7)

NameAmylin, rat
Code[124447-81-0]
The aliasAmylin, rat
Sequence (single letter abbreviation)KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY-NH2(C2&C7 bridge)
Sequence (three-letter abbreviation)H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2(trifluoroacetate salt)(Cys2 and 7 bridge)
A basic descriptionAn amylin receptor antagonist that attenuates the ANP release in streptozotocin-treated rats.
solubility 
The molecular weight3920.5
Chemical formulaC167H272N52O53S2
The purity80%,90%,95%,98%,99%
Weight1mg,5mg,10mg,50mg,100mg,1g
Storage conditionsStore at -20°C. Keep tightly closed. Store in a cool dry place.
Annotation 
Documents 
Figures 
ReferenceE.R.Szabo et al., FASEB J., 26, 272 (2012) J. Asai et al., BBRC, 164, 400 (1989) J.Green et al., J. Mol. Biol., 326, 1147 (2003) J.D.Leffert et al., Proc. Natl. Acad. Sci. USA, 86, 3127 (1989) H.A.Golpon et al., Peptides, 24, 1157 (2003)
The C-terminal 
The N-terminal 
Chemical bridge(Cys2 and 7 bridge)

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CAS:85466-18-8|Thymopoietin II (32-35)|RKDV

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β-Amyloid (1-42), human|DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

Contact: Liven Qian(钱叶华)-Custom Peptide Mobile: 13761298676(微信) Email:cps037@chinapeptides.net QQ:2880526724 ChinaPeptides Co., Ltd./强耀生物科技有限公司   04010011526 β-Amyloid (1-42), human DAEFRHDSGYEVHHQKLVFFAEDV GSNKGAIIGLMVGGVVIA Number of Residues: 42 1-Letter Code: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA 3-Letter Code: Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala Molecular weight (Mr): 4513.12 g/mol Isoelectric point: 5.8 Net charge at pH 7.0: -1.7 Average hydrophilicity: -0.1 Ratio of hydrophilic residues / total number of residues: 31 %    Name beta-Amyloid (1-42), recombinant Code   The alias beta-Amyloid (1-42), recombinant Sequence (single letter abbreviation) DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA Sequence (three-letter abbreviation) H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-...

The therapeutic effect of anti-CD52 treatment in murine experimental autoimmune encephalomyelitis is associated with altered IL-33 and ST2 expression levels

文献作者:Mark Barbour, Rachel Wood, Shehla U.Hridi, Chelsey Wilson, Grant McKay, Trevor J.Bushell, Hui-Rong Jiang   《Journal of Neuroimmunology》 ABSTRACTS Experimental autoimmune encephalomyelitis  (EAE) mice were administered with murine anti-CD52  antibody  to investigate its therapeutic effect and whether the treatment modulates IL-33 and ST2 expression. EAE severity and  central nervous system  (CNS) inflammation were reduced following the treatment, which was accompanied by peripheral  T and B lymphocyte  depletion and reduced production of various  cytokines  including IL-33, while sST2 was increased. In spinal cords of EAE mice, while the number of IL-33 +  cells remained unchanged, the extracellular level of IL-33 protein was significantly reduced in anti-CD52 antibody treated mice compared with controls. Furthermore the number of ST2 +  cells in the spinal cord of treated EAE mice was  downregulated ...